Not known Factual Statements About phenobarbital sodium drug class
Not known Factual Statements About phenobarbital sodium drug class
Blog Article
pentobarbital will lower the level or effect of naloxegol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Utilization of naloxegol with sturdy CYP3A4 inducers isn't advisable
pentobarbital will decrease the level or effect of sunitinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
Animal info. Phenobarbital sodium is carcinogenic in mice and rats after lifetime administration. In mice, it created benign and malignant liver cell tumors. In rats, benign liver mobile tumors ended up noticed incredibly late in life.
pentobarbital will decrease the level or effect of bazedoxifene/conjugated estrogens by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
DOSAGE AND ADMINISTRATION Dosages of barbiturates need to be individualized with complete expertise in their specific properties and advisable level of administration.
pentobarbital will decrease the level or effect of tadalafil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Stay away from mix in pulmonary HTN patients. For clients with ED, check reaction to tadalafil meticulously as a consequence of prospective for lessened effectiveness.
pentobarbital will minimize the level or effect of etravirine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will minimize the extent or effect of fostemsavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will decrease the level or effect of montelukast by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Not known.
In 2014, Oklahoma used a combination of pentobarbital, potassium chloride and vecuronium bromide to execute convicted murderer Michael Lee Wilson. Given that the drugs were administered Wilson reported, “I feel my whole entire phenobarbital sodium package insert body burning” just before he died.
pentobarbital will decrease the level or effect of venetoclax by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
fentanyl intranasal and pentobarbital both boost sedation. Keep away from or Use Alternate Drug. Restrict use to clients for whom alternative treatment options are insufficient
pentobarbital will reduce the level or effect of tofacitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. Lack of, or reduced response to tofacitinib may well occur when coadministered with powerful CYP3A4 inducers
pentobarbital will minimize the extent or effect of midazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.